Neurons and Exercise

Neurons and Exercise

Friday, February 8, 2019

Autism Chapter from Silica Water the Secret of Healthy Blue Zone Longevity in the Aluminum Age


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Autism

The links between autism and aluminum accumulation in the brain were described in my 2016 book “Prevent Alzheimer’s, Autism, and Stroke”1.  Autism is a modern mismatch disease in which our evolved mechanisms for aluminum protection are failing to protect us from an exponential increase in environmental aluminum exposure.  For this reason we are witnessing an epidemic of autism with the rate of autism in the population increasing exponentially since it was first discovered by Leo Kanner in 1938 (see Figure 23).
 
Figure 23 - Autism growth in the U.S plotted with aluminum production worldwide1,227-229,234-237
 

Unfortunately aluminum absorption by the brain begins early in life.  Aluminum is transferred from the maternal blood circulation to the fetal blood circulation via the placenta311. The brains of three fetuses, one full-term infant, and three premature infants from two to six months were analyzed for aluminum. These brains had a mean aluminum concentration of 1.2mcg per gram dry-weight of brain tissue with a standard deviation of 0.2mcg per gram312.  Aluminum levels have been found to rise in the brains of fetuses during gestation and they rise the highest immediately after birth313.  The blood-brain barrier that protects the brain is incompletely developed at birth and is even less mature in the human embryo.
Aluminum is introduced into the bodies of children by:
·         Vaccinations with vaccines containing aluminum as an adjuvant
·         Intestinal absorption from food, such as baby formula, colored candy, baking powder, drinking water, and a variety of pharmaceuticals, such as antacids
·         Absorption through the skin from antiperspirants, astringents, cosmetics, and sunscreens
Aluminum salts injected into the body by vaccination slowly leach into the blood stream1.  Approximately 50% of children with autism have increased intestinal permeability that is not seen in children without autism129. After a metal ion, such as aluminum, is ingested and absorbed by the intestine it becomes dissolved in the blood. Some of the metal is absorbed from the blood by the brain. Also an aluminum salt applied to the skin can become dissolved in the blood. These routes of aluminum accumulation may be causal factors in childhood developmental regression of a subgroup of those with autism (approximately 25%) that lose skills as they age314.  
In 2012 an analysis was performed on hair from 44 children, age 3 to 9 years, diagnosed according to DSM-IV with ASD.  It was discovered that the mean value for aluminum in the hair of autistic children (15.2mg/kg) was 90% higher than aluminum in the hair of non-autistic children (8.0mg/kg)130. This was the first analytical data linking high levels of accumulated aluminum to autism.  In 2015 a second study demonstrated that aluminum levels in the hair of autistic children are higher than aluminum levels in non-autistic children.  In this study the source of aluminum was traced to the use of aluminum cookware315.
In 2017 an analysis was performed in Professor Christopher Exley’s laboratory on the brains of 5 individuals with confirmed ASD, 4 males and 1 female. The mean and standard deviation (in parenthesis) of aluminum content across all five individuals for each lobe were 3.82(5.42), 2.30(2.00), 2.79(4.05) and 3.82(5.17) mcg per gram dry weight for the occipital, frontal, temporal and parietal lobes respectively. The highest amount of aluminum detected was 8.74 mcg per dry weight in the occipital lobe of a 15 year old boy. These are some of the highest aluminum levels in the brain yet recorded and clearly link aluminum accumulation with the autistic brain65.  
In the brains of those with autism it has been found that the brain regions most impacted include the hippocampal complex and entorhinal cortex316. These areas of the autistic brain have smaller and less complex neuronal networks than normal316. This suggests a curtailment of normal neuron development and neuronal connectivity.  These areas of the brain are also responsible for memory, learning, emotion, and behavior, disturbances of which comprise the core clinical features of autism317.  Most importantly these are the same brain regions found to be hot spots for aluminum accumulation in the brain266.  Glial cells that comprise part of the blood-brain-barrier were also found to be aluminum hotspots in the autistic brain65.
In 2018 a biochemical classification of children has been found to have high (88%) reliability for diagnosing those with ASD318.  This biochemical classification is based primarily on low levels of metabolites from two biochemical pathways serving as biomarkers of ASD:
·         Folate dependent one-carbon metabolism (FOCM)
·         Transulfuration (TS)
Both of these pathways are inhibited directly and indirectly by aluminum1,100,101. Therefore low levels of these metabolites are biomarkers for both aluminum toxicity and ASD455. The reliability of this biochemical classification of children is more supportive information that aluminum accumulation is a causative factor of autism.  
There has been no published study of silica water supplementation for elimination of some symptoms of autism. However, there is reason to believe that silica water may work to lower aluminum levels in autistic children and heal some symptoms of autism. The following is anecdotal information from Facebook provided by parents who gave their children OSA rich silica water for 3-8 months:
1.      I have become fascinated with this subject and the unbelievable simplicity of drinking a silicon rich mineral water to remove aluminum from the body since discovering Prof Chris Exley's excellent work at the end of 2017. We have been using this on our 9 yr. old son who has an ASD (Autism Spectrum Disorder) diagnosis and we saw clear cognitive improvements with him after 3 months on Volvic water. There were improvements to his mood, his laughing. He was more happy and had more speech, asking significantly more questions (this is MASSIVE!), and more imaginative play. … After 6 months on Volvic we switched to Fiji for the last two months and have seen dramatic improvements. He is so much calmer, better memory, understanding things more, eating more things and generally is eating more and will sit for dinner without requiring distractions, is laughing loads and showing emotions more, and is making progress which his teachers and tutors are also seeing. It's amazing to see! We have tried almost every protocol going since he was 3 and can confirm this is no placebo effect. This works, and is working for us and we hope more people try it with literally no down side. Amazing stuff! September 2018

2.      “My son is 21 and has autism. I started giving him Fiji water about 3 to 4 months ago. I didn't make him drink a certain amount or anything. He just drank it when he was thirsty, though he has always been a big water drinker. I didn't expect too much, but I can honestly say that I've noticed a difference! Mostly in the past month. I don't know how to explain it other than say he is more aware. Our conversations are getting to be more interactive. He initiated an ‘I love you’ for the first time in 21 years!!! Tonight, he said ‘Thank you Mom, you're the best!!’. This is not typical for my son. Not because he didn't feel that way, he just never expressed it verbally before. I'm not saying this to promise other parents that you will get the same results, but I'm very grateful for what we have experienced so far. I now buy a few cases of Fiji water a month as I truly believe it is helping”. July 2018 
The following anecdotal information from Facebook is provided by parents who saw improvement after giving their children silica rich water for just 6 to 8 weeks:  
1.      “My daughter who is 12 has a moderate intellectual disability diagnosis as well as regressive autism level 2.  She also had absence seizures and non-functional speech.  Since starting Fiji water 6 weeks ago, 1/2 liter per day, she has been pointing to people and objects and commenting about them or asking questions - sharing an interest - the beginnings of conversation (which also had disappeared as she regressed). There has been a major change in her auditory processing as she now hears and responds to all speech. She is learning, retaining, and using information.  Absence seizures have stopped, she is making eye contact, and receptive language has improved greatly where she now can follow 2-3 part instructions. I have seen changes in awareness, alertness, connection with others, conversation, and comprehension.  It was like a light switched on.   We have started and stopped the Fiji water especially initially.  Improvements eased a bit upon stopping the Fiji protocol and picked up again upon restarting.   I’ve done a lot for my daughter over the years but this has been by far the easiest intervention to apply with the most far reaching results across all areas for her”. February 2018

2.      “My 9 year old son has really struggled with reading. All of the sudden his reading skills have just taken off!! To the point his teacher wanted to talk to me after school! She said he has improved so much in the past 2 weeks she wanted me to know how proud she was of him! It is amazing he has only been on the silica water for about 6 weeks so I can’t wait to see what the future holds.” February 2018


3.      My 6 year old son has been drinking about ½ liter a day of Fiji and I’ve seen big improvements in his behavior. Also much more affectionate. My dad commented that it’s like he’s grown up 2 years in the last couple months. August 2018

4.      “I have been using Fiji water for my 3.5 year old son for the last 6 weeks. He is autistic and was preverbal. After starting Fiji water, there is a lot of improvement in his speech, understanding of language and memory. He seems to have lost a bit of his chubbiness, no other negatives so far.” April 2018

5.      “We have been using Silicade. After 4 weeks my 7 year old autistic son showed no signs of improvement. But after 8 weeks on Silicade his hyperactivity had decreased allowing him to attend an entire church service. After 12 weeks he is continuing to improve, and I'm starting to worry that the special school section he's in may notice and kick him out!
Note: Silicade is homemade synthetic silica water with the same level of OSA as Fiji water. A recipe for Silicade is in Chapter 6.
The loss of weight (i.e. “lost … his chubbiness”) seen in some children and adults after starting on silica water is likely due to a rise in L-carnitine in the blood.  L-Carnitine acts as a chaperone that facilitates the transfer of stored fat as fatty acids (i.e. triglyceride) into the mitochondria so they can be oxidized and metabolized for energy production. Both the production of L-carnitine and the oxidation of fatty acids are suppressed by aluminum toxicity resulting in increased BMI, as described previously in this chapter299-302,319.  
Approximately one in five autistic children with intellectual disability and one in twelve autistic children without intellectual disability have epileptic seizures320. The anecdotal information that “absence seizures have stopped” has been followed by others who have also observed more control over seizures with silica water:
“My 6 year old son has epilepsy, acute confusionary migraines and autism.  He has been drinking silica water and not only are his seizures and migraines much better controlled but he has gone from being more 2-3yr old level to almost right with his peers in most areas. Still he is academically delayed but actually learning now, he wasn't before.” Feb. 2018
This anecdotal information is encouraging and gives us hope that OSA rich drinking water allows the brain to heal from aluminum accumulation and provides recovery from autism.  Of course supplemental silica water is only the first step. A diet high in silica rich vegetables (see Chapter 4) and avoidance of aluminum ingestion (see Appendix II) are both suggested for ultimately stopping neurodegeneration by removing aluminum from autistic children’s brains. 

Autism Due to Vaccine Injury

Children’s body-burden of aluminum from vaccinations exceeds that from dietary sources, such as baby formula1,321,322.  By comparing ASD prevalence in 7 developed countries, it has been shown that both the number of aluminum containing vaccinations and the scheduling of these vaccinations during the first 4 months of a child’s life is strongly correlated with ASD prevalence. Those countries, such as Sweden, Iceland, and Finland, who schedule no aluminum containing vaccinations from birth to 3 months of age, have less than half the ASD prevalence when compared to the U.K. and the U.S.A. where babies are given aluminum containing vaccinations from birth to 2 months of age323.  In addition, a positive correlation was found between autism prevalence and childhood vaccination uptake across the U.S.A. population324.   
It is estimated that aluminum accumulation due to childhood vaccination may be causal a factor in childhood developmental regression of a subgroup of those with autism (approximately 25%) that lose skills as they age324. Here is anecdotal information from Facebook on how silica water can turn around this regression due to aluminum in vaccines:
1.      “The reason I have got so interested in silica water is because of my grandbaby. He will be 2 in September. We believe he is vaccine injured because he completely stopped all talking and jabbering after his 1 year vaccines. He has gone backwards it seems. I first came across diatomaceous earth, then Fiji water, and now the local silica rich spring water. My daughter mixes his tea and juice with the silica water. I can say without a doubt it has changed him. He can now look you in the eyes, but before he would not make any eye contact. He has started jabbering more. My daughter texted me last night saying ‘Mama it's like I have a completely different baby he is looking at me and jabbering and trying to say mama again’. So we are keeping this all up in hope's we get our little man back. But no more vaccines for us. She is still breastfeeding and I feel that has helped him a lot as well as keeping his immune system up.” August 2018

2.      My son, aged 9, has severe autism which he developed after vaccination. It took about 6 months from this final vaccination for my son to go from a loving normal developed boy to having full blown Autism. Our boy was in fact gone, replaced by a stranger. I saw Dr. Exley's report on silica water and though we might as well give it a go. …  I switched my son to Volvic Water about 4 weeks ago, within the first week we noticed slight improvements - good eye contact, sitting for longer, more verbal and is singing along to more adverts, some appropriate speech, and I actually got a cuddle and a kiss from him. … My son is currently on Day 32 of drinking silica water (Acilis mainly, sometimes Volvic). He is currently very calm, reciting TV adverts, full of smiles, looking though his DVDs. I plan to carry on giving my son Acilis Silica Water. At the moment we have experienced no negatives of switching to silica water. I don’t think my son would have improved this much or at all within this short timeframe (8 weeks). … We get little improvements every now and then, but for this amount of improvement it would have taken at least 2 - 3 years-worth of hard work and still doubtful that he would have improved this much without the silica water. It is definitely the silica water that is all that is different with his diet. After 3 days of drinking it, very subtle things started happening and after one week, there was no way I was going to stop the water. I too was skeptical of whether this would work as you hear so many stories and things to try and not much seems to do anything, but silica water should be on prescription to ASD kids.” Sept.2018

I recommended that mothers drink OSA silica water when breastfeeding.  It has been shown that the mother gives almost all her silica to the baby during and immediately after pregnancy (see Figure 8)85.
Look for aluminum or alum containing vaccines in Table 37 or for a more up-to-date table: https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/b/excipient-table-2.pdf 


Conclusion of Autism Aluminum has been found in non-autistic brains of human fetuses, one full-term infant, and premature infants. These brains had a mean aluminum concentration of 1.2mcg per gram dry-weight of brain tissue with a standard deviation of 0.2mcg per gram311,312 This demonstrates that aluminum from the mother’s blood is transferred to the fetal blood circulation via the placenta and some of this aluminum normally accumulates in the fetuses’ and infant’s brains.
Two studies have found higher than normal aluminum levels in hair samples from autistic children.  In addition, higher than normal aluminum levels (2.3 to 3.8 mcg per dry weight) have been found in the following regions of autistic brains: occipital, frontal, temporal and parietal lobes65.   These regions of the brain known to be hot spots for aluminum accumulation266 are the same areas of the brain that are responsible for memory, learning, emotion, and behavior, disturbances that comprise the core clinical features of autism316,317.  These regions of the autistic brain have smaller and less complex neuronal networks than normal316. Therefore, since aluminum is a known neurotoxin, aluminum can be considered a casual factor of autism. 
It is likely that aluminum accumulation due to childhood vaccination is a causal factor in childhood developmental regression of a subgroup of those with autism (approximately 25%) that lose skills as they age314.  Aluminum is used as an adjuvant in many of the vaccines given to children (table 37).  Aluminum containing vaccines have been linked to an increased prevalence of autism and seizures. OSA rich silica water taken by mother and baby has been shown to heal autism and childhood developmental regression that is likely caused by aluminum in vaccines.
Anecdotal information suggests that a diet that includes silica rich drinking water allows the brain to heal from aluminum accumulation and provides healing from autism. It is likely this occurs due to OSA’s ability to facilitate the elimination of aluminum from the brain.